Anti diabetic activity of Acerola Juice
In a study done in the Medical School of Medicine of Marília, Faculty of Technology and Foods of Marília, Avenida Higino, Brazil. the effects of acerola juice in the lipid metabolism and glycemic profile in rats were investigated. Results have shown that the diabetic induced rats treated with acerola juice showed significantly decreased levels of glucose, cholesterol, triglycerides, and increased HDL-c. The study further suggests that acerola juice is maybe a potential strategy to aid in the prevention of DM and dyslipidemia and its complications or to act as an auxiliary in the treatment of these diseases. http://www.ncbi.nlm.nih.gov/pubmed/21318139
Skin-lightening effect of a polyphenol extract from Acerola (Malpighia emarginata DC.) fruit on UV-induced pigmentation.
The Journal of Bioscience, Biotechnology, and Biochemistry. Dec 2008 published a research from Nichirei Foods Inc, Chiba-shi, Chiba, Japan that investigated the physiological functions of polyphenols from acerola (Malpighia emarginata DC.) fruit. In the experiment, the crude polyphenol concentrated extract from acerola (C-AP) was used to examine the skin-lightening effect on brownish guinea pigs which had been subjected to controlled UVB irradiation. The results show that C-AP significantly lightened the UVB-irradiated skin pigmentation. Furthermore, treatment with C-AP reduced the content of melanin in B16 melanoma cells, suggesting that the in vivo skin-lightening effect of C-AP was due to the suppression of melanin biosynthesis in melanocytes.
This investigation suggests that an oral ingestion of C-AP may be efficacious for reducing UVB-induced hyper-pigmentation by inhibiting the tyrosinase in melanocytes. http://www.ncbi.nlm.nih.gov/pubmed/19060403
Biological activity of barbados cherry (acerola fruits, fruit of Malpighia emarginata DC) extracts and fractions
The Journal of Phytotherapy Research. March 2004, published a study done i the.Pharmaceutical University, Noshio, Kiyose, Tokyo, Japan. on the biological activity of acerola fruits and its fractions. The study showed that organic extract of acerola fruit showed higher cytotoxic activity against tumor cell lines such as human oral squamous cell carcinoma (HSC-2) and human submandibular gland carcinoma (HSG), when compared with that against normal cells such as human periodontal ligament fibroblasts (HPLF) and human gingival fibroblasts (HGF). Moreover it also displayed higher tumor-specific cytotoxicity showing higher multidrug resistance (MDR) reversal activity, than verapamil as positive control. The study suggests that the tumor specific cytotoxic activity and MDR reversal activity of barbados cherry (acerola) may have possible application for cancer therapy. http://www.ncbi.nlm.nih.gov/pubmed/15103668
Acerola extract Benefits against Age-related diseases
The Journal of Anticancer Reasearch July 2003, published a study done in the Faculty of Science, Josai University, Sakado, Saitama, Japan, on the biological activities of acerola extracts on the prevention for age-related diseases. The study investigated the effects of acerola extract on nitric oxide production by macrophages. It showed that the acetone extract exhibited a high inhibitory activity of nitric oxide production. There was a notable scavenging of radical species such as superoxide anion (O2) and nitric oxide radicals. These results suggest that acerola extract is a viable and natural alternative to prevent age-related diseases. http://www.ncbi.nlm.nih.gov/pubmed/12926058